2022

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci

Deak JD, Zhou H, Galimberti M, Levey DF, Wendt FR, Sanchez-Roige S, Hatoum AS, Johnson EC, Nunez YZ, Demontis D, Børglum AD, Rajagopal VM, Jennings MV, Kember RL, Justice AC, Edenberg HJ, Agrawal A, Polimanti R, Kranzler HR, Gelernter J. Molecular Psychiatry. doi: 10.1038/s41380-022-01709-1

Cross-ancestry genomic research: time to close the gap

Atkinson EG, Bianchi SB, Ye GY, Martínez-Magaña JJ, Tietz GE, Montalvo-Ortiz JL, Giusti-Rodriguez P, Palmer AA, Sanchez-Roige S. Neuropsychopharmacology doi: 10.1038/s41386-022-01365-7

A phenome-wide association study of polygenic scores for attention deficit hyperactivity disorder across two genetic ancestries in electronic health record data

Niarchou M, Sealock JM, Straub P, Sanchez-Roige S, Sutcliffe JS, Davis LK. Neuropsychiatric Genetics doi: 10.1002/ajmg.b.32911

Polygenic Transcriptome Risk Scores Can Translate Genetic Results Between Species

Santhanam N*, Sanchez-Roige S*, Liang Y, Chitre AS, Munro D, Chen D, Cheng R, Gao J, George AM, Gileta A, Holl K, Hughson A, King CP, Lamparelli AC, Martin CD, Martinez AG, Mi S, St. Pierre CL, Tripi J, Wang T, Chen H, Flagel S, Ishiwari K, Meyer P, Saba L, Solberg Woods LC, Polesskaya O, Palmer AA, Im HK bioRxiv *joint first authors doi: 10.1101/2022.06.03.494719

Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities

Mallard TT, Linner RK, Grotzinger AD, Sanchez-Roige S, Seidlitz J, Okay A, de Vlaming R, Meddens SFW, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Palmer AA, Davis LK, Tucker-Drop EM, Kendler KS, Keller MC, Koellinger PD, Harden KP Cell Genomics In press.

Accelerating opioid use disorders research by integrating multiple data modalities

Identifying high-risk comorbidities associated with opioid use patterns using electronic health record prescription data

Jennings MV, Lee H, Rocha DB, Bianchi SB, Coombes BJ, Crist RC, Faucon A, Hu Y, Kember RL, Mallard TT, Niarchou M, Poulsen MN, Straub P, Urman RD, Walsh CG, PsycheMERGE Substance Use Disorder Workgroup, Davis LK, Smoller JW, Troiani V, Sanchez-Roige R Complex Psychiatry doi: 10.1101/2021.11.23.21266717